In what episode does George die?
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After a desperate attempt by doctors to save George’s life, he dies in the OR during his surgery with a swollen brain. His work colleagues are shocked and deeply saddened by this event. His identity came into question when Lexie denied it was George, his ex-wife Callie however remembered a freckle he had on his hand the shape of Texas. The freckle was found which confirmed his identity. O’malley’s organs were all donated with consent from his mother and with the help of Izzie.